Xenopus laevis (the African clawed frog) oocytes are a popular model system for a wide variety of biological studies. Microinjection of DNA or messenger RNA (mRNA) into the Xenopus oocytes leads to the functional expression of the encoded proteins. The proteins expressed in such a new environment can be functionally characterized under well-deļ¬ned conditions. This makes oocytes an important expression system for studies of molecular biology and electrophysiology. Such an in vitro expression system is particularly suitable for studying not only the structure and functions of cloned and mutated proteins but also the physiology of neurotransmitter receptors, ion channels, and transporters. Xenopus Oocyte Screening Model
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